Bacteriophage Engineering

Bacteriophage Engineering

Aurelija has been the driving force behind this work.  This has included the optimisation of methods to engineer the genome of bacteriophage T7 using CRISPR systems for selection of phage mutants.

Also in collaboration with the group Dominic Sauvageau, Aurelija has been engineering the genome of bacteriophage T4 using marker-based selection. Results to date have shown phage engineering can provide a mechanism to expand the number of bacterial species phage can kill.